A Comprehensive Study on Provesicular Drug Delivery System: Proniosomal Gel

Vesicular approaches are novel techniques for transporting the drug that reinforces availability of drugs and gives an action a prolonged time. Besides, it has definite advantages over traditional delivery systems. Liposomes niosomes comprising vesicles demonstrate stability issues such as aggregation, leakage, fusion sedimentation due to aqueous nature system. The provesicular system developed overcome these problems unique approach includes proliposomes proniosomes. Provesicles dry, anhydrous formulations, coated with non-ionic surfactant, acts carrier mixed water when needed. This article reviews systems focus on composition, preparation, mechanism delivery, encapsulation into provesicles characterization techniques. Likewise, this review details summary research findings patent reports proniosomal investigations. As supported by literature study, proniosomes leading various different routes administration.